Albuminuria and its correlates in an Iranian type 2 diabetic population

ObjectiveTo study the prevalence and correlates of increased urinary albumin excretion (UAE) in an Iranian type 2 diabetic population.Methods:Over a one year period since October 2002, 400 consecutive type 2 diabetic patients referred to an outpatient diabetes clinic, were enrolled in a cross sectional study. Subjects had no history of renal impairment or overt proteinuria. Data concerning demographic characteristics and cardiovascular risk factors were recorded and height, weight and blood pressure were measured. Glucose, cholesterol, HDL-C, LDL-C, triglyceride, apoprotein B, lipoprotein a, creatinine, and HbA1c were measured in fasting blood samples. Overnight twelve-hour UAE were assessed by immunoturbidometry method. Regression analyses were employed to determine the correlates of UAE.Results:Out of 400 patients, 156 (40%) subjects had increased UAE (UAE [greater than or equal to]30mg/24hour). The UAE was higher in males compared to females (145.5 vs. 72.1 mg/day; p