UroToday.com - This paper reports the results of a saturation biopsy protocol of 36 cores performed on 48 autopsied prostates from deceased men without any past history of prostate cancer. The first 18 cores were taken in the mid peripheral zone (6 cores), the lateral peripheral zone (6 cores) and the central zone (6 cores).

A new, independently-conducted study being presented at AASLD shows that PEGASYS(R) (peginterferon alfa-2a (40KD)) regimens result in higher cure rates for hepatitis C patients compared to regimens with another pegylated interferon.(1) Comparing Today's Standard Treatment Regimens: The Milan Safety Tolerability Study Prof.

With only a few days remaining before Election Day, researchers from Harvard School of Public Health and the Kaiser Family Foundation, writing for the November 6, 2008, New England Journal of Medicine, find that seven in ten registered voters say major changes are needed in the U.S. health care system. The article, written by Robert J. Blendon, Sc.D.

Two biologists at the University of California, San Diego have discovered the first of a new class of cellular motor proteins that "rewind" sections of the double-stranded DNA molecule that become unwound, like the tangled ribbons from a cassette tape, in "bubbles" that prevent critical genes from being expressed.

Mammalian cells with extra chromosomes share some common traits that could be exploited to develop cancer treatments, according to MIT biologists. Having too many chromosomes, a condition known as aneuploidy, wreaks havoc on an organism, usually resulting in birth defects or death. However, it seems to confer an advantage on tumor cells, which are nearly always aneuploid.

Sometimes it's hard to tell friends from foes, biologically speaking. Naturally produced in the body, urokinase plasminogen activator and plasminogen interact to break up blood clots and recruit clean-up cells to clear away debris related to inflammation. In fact, urokinase manufactured as a drug effectively clears clogged arteries by generating clot-busting plasmin from blood-derived plasminogen.

New research from the University of Bristol brings stem cell therapies for heart disease one step closer. The findings reveal that our bodies' ability to respond to an internal 'mayday' signal may hold the key to success for long-awaited regenerative medicine.

MONTEREY, CA, USA (UroToday.com) - In his State-of-the-Art talk, Colin Collins discussed biomarkers for prostate cancer (CaP) risk stratification. He asked where genome copy number profiles can predict CaP recurrences. To explore this, his group used array comparative genomic hybridization (CGH) to identify genes mutations.

Patients who will be subjected to new compulsory powers under the Mental Health Act from today (3 November) face being denied access to critical support and protection, says mental health charity Mind.

MONTEREY, CA, USA (UroToday.com) - A State-of-the-Art lecture by Erik Castle addressed the question of whether robotic cystectomy was ready for "prime time." Prime time was defined as an operation that is equivalent to open surgery, reasonable, reproducible, and teachable.

The Department of Health today urged Primary Care Trusts (PCTs) to engage better with patients and the public in developing plans and making decisions about local health services. New guidance, published today, will help the public have more say in decisions made by their PCT, enabling them to shape local health services.

MONTEREY, CA, USA (UroToday.com) - In this session, Christopher P. Evans presented a State-of-the-Art lecture on molecular targets in prostate and renal cancers. Molecular targets in cancer diagnosis and therapy have come to the fore of the oncology field in the last decade.

Dr Asif Chatoo of LLOC along with Dr Zaki Kanaan and Dr James Goolnik Spotlight the Patient Experience At the BACD Fifth Annual Conference 2008.

MONTEREY, CA, USA (UroToday.com) - Margaret Pearle presented a State-of-the-Art lecture on the metabolic aspects of urolithiasis at the 84th annual meeting of the Western section of the AUA. In light of the available interventional treatment options, she pointed out that many questioned the need for medical management.

The World Health Organization and Italy will be sending 10 tonnes of medical supplies to help the tens of thousands of people affected by the ongoing insecurity in eastern Democratic Republic of Congo. Intensive efforts are needed to prevent the spread of communicable diseases among the fleeing population and to treat the physical trauma caused by the violence.

Researchers at Huntsman Cancer Institute (HCI) believe they may be one step closer to understanding how certain forms of colon cancer develop. In a study using siblings who have been diagnosed with colon cancer, scientists discovered similarities on a region of a particular chromosome, referred to as 7q31.

MediQuest Therapeutics, Inc. received a Complete Response letter from the U.S. Food and Drug Administration (FDA) Division of Cardiovascular and Renal Products for its New Drug Application (NDA) 22-241 (covering Vascana® [MQX-503], a proposed topical therapy for Raynaud's Disease).

Patients with diabetes who participate in a program combining aerobic and high-force eccentric resistance exercise demonstrate improvements in glucose control, physical performance, and body fat composition, according to a study published in the November 2008 issue of Physical Therapy (PTJ), the scientific journal of the American Physical Therapy Association (APTA).

UroToday.com - Protocol 30846 of the EORTC-GU Group recruited 234 patients with histologically proven lymph node positive disease (pN1-3) according to the TNM classification of 1992. This included regional but not para-aortic lymph node disease.

UroToday.com - In 1999, Kim et al. from Baylor College of Medicine reported promising potency results from bilateral interposition of sural nerve grafts after bilateral non nerve sparing radical prostatectomy (RP). Our institution was able to duplicate these findings in the bilateral graft model as well.