Background:Compared to the design of a traditional multi-radius (MR) total knee arthroplasty (TKA), the single-radius (SR) implant investigated also has a single flexion/extension axis of rotation fixed to the femur. The biomechanical effectiveness of an SR for functional daily activities, e.g., rising from a chair, is not well understood. The purpose of the study was to compare the biomechanics underlying functional performance of the sit-to-stand movement between the limb containing an MR and the other limb containing an SR TKA of bilateral TKA participants.Methods:Three dimensional kinemati

Background:Protein A, protein G and protein L are three well-defined immunoglobulin (Ig)-binding proteins (IBPs), which show affinity for specific sites on Ig of mammalian hosts. Although the precise functions of these molecules are not fully understood, it is thought that they play an important role in pathogenicity of bacteria. The single domains of protein A, protein G and protein L were all demonstrated to have function to bind to Ig. Whether combinations of Ig-binding domains of various IBPs could exhibit useful novel binding is interesting.Results:We used a combinatorial phage library which displayed randomly-rearranged various-peptide-linked molecules of D and A domains of protein A, designated PA(D) and PA(A) respectively, B2 domain of protein G (PG) and B3 domain of protein L (PL) for affinity selection with human IgG (hIgG), human IgM (hIgM), human IgA (hIgA) and recombinant hIgG1-Fc as bait respectively.

Two patients say refunds are owedFayObserver.com, NC - 3 hours agoHis medical license was indefinitely suspended by the board Dec.

Positron emission tomography (PET) scanning may allow non-invasive assessment of the formation of Alzheimer's disease-related plaques in the brain, according to a study released early online on August 11, 2008 in the Archives of Neurology, one of the JAMA/Archives journals. Alzheimer's disease is degenerative neurological disease characterized by dementia.

After returning from service in Iraq and Afghanistan, younger service members and Reserve and National Guard combat personnel are more likely to begin heavy drinking, binge drinking, or other alcohol related problems. These findings are reported in a study published in the August 13 issue of JAMA.

Spouses of husbands and wives with dementia pay an emotional toll as they care for their ailing spouse. This has prompted a call for new interventions and strategies to assist caregivers in coping with the demands of this difficult time, according to a study from Case Western Reserve University's Mandel School of Applied Social Sciences.

Dr. Asher Kimchi, Founder and Chairman of the International Academy of Cardiology announced the winners of the 2008 IAC Awards at the 14th World Congress on Heart Disease held in Toronto. Dr. Kimchi, together with Dr. Jeffrey S.

PolyMedix, Inc. (OTC BB: PYMX), an emerging biotechnology company developing new therapeutic drug products to treat infectious diseases and acute cardiovascular disorders based on biomimetics, has clearance to start human clinical trials in the United States with its anticoagulant reversing agent PMX-60056 under the Investigational New Drug application (IND) filed with the U.S.

The Swedish biotech company AbSorber has been given clearance by the U.S. Food and Drug Administration (FDA) to market and sell its XM-ONE® transplantation test in the U.S. Initially, sales of XM-ONE® in the U.S. will target the kidney transplantation market valued at approximately SEK 200 million. XM-ONE® previously received CE marking and is approved for sales within the EU.

Oxygen Biotherapeutics, Inc. (OTCBB:OXBO) announced that the company has developed a gel-like form of Oxycyte® that it intends to investigate as a topical application for open wounds, abrasions and burns. Oxycyte is the Company's perfluorocarbon (PFC) therapeutic oxygen carrier. The innovation is based on technologies in-licensed earlier this year from Virginia Commonwealth University.

Gilead Sciences, Inc. (NASDAQ:GILD) announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Viread® (tenofovir disoproxil fumarate) for the treatment of chronic hepatitis B, a serious liver disease caused by the hepatitis B virus (HBV).

After failure of 1st generation thrombopoietic growth factors due to immunogencity, the 2nd generation is focused on oral TPO mimetics, now followed by a 3rd generation of engineered biologics with potential for higher potency and efficacy The Business Intelligence firm La Merie S.L.

Regular running slows the effects of aging, according to a new study from Stanford University School of Medicine that has tracked 500 older runners for more than 20 years. Elderly runners have fewer disabilities, a longer span of active life and are half as likely as aging nonrunners to die early deaths, the research found.

tropical diseases AID Exxon Mobil Corporation (NYSE:XOM) announced a $3.5-million grant to the Global Health Group at the University of California, San Francisco (UCSF), to expand its core support for an unprecedented malaria elimination effort in southern Africa. "To win the fight against malaria we must attack the disease on many fronts," said Rex W.

The following statistics were released by the Department of Health: GP extended opening hours for month ending July 2008. This data shows the number of GP practices within each Commissioner area (PCTs and Care Trusts) and how many of those practices were offering extended opening hours on the census date (21st July 2008).

GammaCan International, Inc. (OTCBB: GCAN), a developer of proprietary immunotherapies for the treatment of melanoma and other cancers, announced further progress in its VitiGam™ development program. In preparation for its upcoming IND submission for VitiGam™, the Company successfully completed additional experiments using its established mouse melanoma model.

As nearly one billion poor people worldwide struggle to survive the unrelenting global high food and fuel price crisis, the United Nations World Food Programme (WFP) announced the roll-out of a US$214 million package directed at 16 hunger hotspots.

In middle and older ages, running may be associated with reduced disability and increased survival, according to a report released on August 11, 2008 in the Archives of Internal Medicine, one of the JAMA/Archives journals. The United States, largely thanks to innovations in medical technologies, has made a major shift to a generally older population.

Over the age of 75 years, men should no longer be screened for prostate cancer, according to recommendations from the U.S. Preventive Services Task Force published on August 5, 2008 in the Annals of Internal Medicine.

In comparison with Canadians, Americans with vision problems are equally or more likely to access eye care services, if they have health insurance. Without health insurance, Americans visit eyecare professionals at lower rates, according to a report released August 11, 2008 in the Archives of Ophthalmology, one of the JAMA/Archives journals.