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Assignment of Streptococcus agalactiae isolates to clonal complexes using a small set of single nucleotide polymorphisms.

Background:Streptococcus agalactiae (Group B Streptococcus (GBS)) is an important human pathogen, particularly of new-borns. Emerging evidence for a relationship between genotype and virulence has accentuated the need for efficient and well-defined typing methods. The objective of this study was to develop a single nucleotide polymorphism (SNP) based method for assigning GBS isolates to multilocus sequence typing (MLST)-defined clonal complexes. Results:It was found that a SNP set derived from the MLST database on the basis of maximisation of Simpsons Index of Diversity provided poor resolution and did not define groups concordant with the population structure as defined by eBURST analysis of the MLST database.

World's Biggest Event On Pain Calls For Palliative Care To Be Made A Human Right

The world's largest event on pain issues and pain management - the 12th World Congress on Pain opened in Glasgow today by calling for palliative pain relief to be made a human right. Outgoing President Troels S.

Statement Of APA President Nada Stotland, M.D. On Abortion And Mental Health

A recently released report on mental health and abortion confirms the position of the American Psychiatric Association: abortion is not a risk to a woman's mental health. APA President Nada Stotland, M.D., an expert on women's mental health, made the following statement today: "As we have known, there is no convincing evidence that abortion is a significant cause of psychiatric illness.

Successful Robot-Assisted Surgery For Urinary Abnormality

Ashok Hemal, M.D., a urologic surgeon from Wake Forest University Baptist Medical Center, and colleagues have reported success using robot-assisted laparoscopic surgery to repair abnormal openings between the bladder and vagina known as fistulas. Reporting on their experience with seven patients, Hemal and colleagues have the world's largest known success with the procedure.

Many U.S. Public Schools In 'Air Pollution Danger Zone'

One in three U.S. public schools are in the "air pollution danger zone," according to new research from the University of Cincinnati (UC). UC researchers have found that more than 30 percent of American public schools are within 400 meters, or a quarter mile, of major highways that consistently serve as main truck and traffic routes.

Dyax Announces DX-88 For Hereditary Angioedema Meets Primary And Secondary Endpoints In Phase 3 Trial (EDEMA4(R))

Dyax Corp. (NASDAQ:DYAX) announced positive topline results from its second Phase 3, placebo-controlled trial, EDEMA4, for its lead product candidate DX-88 (ecallantide) for hereditary angioedema (HAE). The EDEMA4 trial, conducted under a Special Protocol Assessment granted by the U.S.

Nationwide Study Of Landmark Sickle Cell Treatment

Children's National Medical Center immunologist and blood and marrow transplant physician Naynesh Kamani, MD, will serve as the study co-chair for a new national clinical trial of unrelated donor marrow and umbilical cord blood transplants for severe sickle cell disease.

When The Patient Can't Decide: Study Looks At Physician Perspectives On Surrogate Decision Making

Family members are often called upon to make medical choices for patients who are unable to do so themselves. Researchers led by Alexia Torke, M.D., of the Indiana University School of Medicine and the Regenstrief Institute, Inc., studied how physicians treating these patients interacted with surrogate decision-makers.

Cocoa Flavanols Linked To Improved Brain Blood Flow

Cocoa flavanols, the unique compounds found naturally in cocoa, may increase blood flow to the brain, according to new research published in the Neuropsychiatric Disease and Treatment journal. The researchers suggest that long-term improvements in brain blood flow could impact cognitive behavior, offering future potential for debilitating brain conditions including dementia and stroke.

Blood Vessel Gene Influences Brain Size, Yale Researchers Find

The size of a key area of the brain involved in memory and mood disorders is influenced by variation in a growth factor gene that influences blood vessel growth and has been widely studied in heart disease and cancer, Yale University researchers have found.

Oxford Researchers Give Protein Production More Precision

Oxford researchers have developed a new technique to prepare proteins for use as therapeutic drugs. The technology, which represents a significant step forward from current production methods, will enable the development of purer and more effective protein-based drugs.

ASU's Biodesign Institute And ImmuneRegen Collaborate To Investigate Possible Enhancement Of Vaccine Against Norwalk Viruses

ImmuneRegen® BioSciences, Inc., a wholly owned subsidiary of IR BioSciences Holdings, Inc. (OTCBB: IRBS), announced a collaborative relationship with the Biodesign Institute at Arizona State University (ASU), Tempe, Ariz.

Restrictions On The Import Of Unlicensed Melatonin Products Following The Grant Of A Marketing Authorisation For Circadin(R) 2mg

Dear Healthcare Professional, Restrictions on the import of unlicensed Melatonin products following the grant of a marketing authorisation for Circadin® 2mg tablets At the beginning of June 2008, a licensed modified release melatonin product, Circadin ® (Lundbeck), became available in the UK.

If All US States Were As Good As Top 5 States More Children Would Have Health Insurance

According to a 2008 report from the Commonwealth Fund on state-by-state children's health care, if all states performed as well as the five leading states, more children would have health insurance, improved access to care and fewer developmental delays.

Aboriginal Kids Can Count Without Numbers

Knowing the words for numbers is not necessary to be able to count, according to a new study of aboriginal children by UCL (University College London) and the University of Melbourne. The study of the aboriginal children - from two communities which do not have words or gestures for numbers - found that they were able to copy and perform number-related tasks.

Treating Pediatric Voiding Dysfunction

Voiding dysfunction and urinary incontinence in children is common. While these issues can significantly affect quality of life, children are also at an increased risk of urinary tract infections (UTIs), urgency issues and constipation later in life.

Chicago Area Nonprofit Fills Unique Niche For Low-Income Cancer Patients During Chemotherapy

When the doctor told Dionne she had breast cancer, she was stunned. This wasn't supposed to happen. She had children, a husband, and a family that needed her. She would have to undergo extensive chemotherapy, which meant spending money she didn't have. She felt scared, worried, and angry. But mostly, she felt alone. But help was just around the corner.

Chondroitin Sulfate Proteoglycan May Have Many Roles In Spinal Cord Injury Repair

The proteoglycan chondroitin sulfate (CSPG) plays an important role not just in the formation of the glial scar but also in the repair of spinal cord injury, according to an article released on August 18, 2008 in the open-access journal PLoS Medicine.