MEDDOT.COM - Medical News

Aneurysm of an autologous aorta to right coronary artery reverse saphenous vein graft presenting as a mediastinal mass: a case r

admin — Thu, 20 Nov 2008 15:02:39 -0500

Aneurysmal dilation of saphenous vein grafts is a relatively rare complication of the now common surgical procedure of coronary artery bypass graft (CABG) surgery. The true prevalence of this condition is not clear, however, literature review by Jorgensen et. al. between 1975 and 2002 revealed only 76 published cases. Recent review of literature, utilizing OVID (search terms: saphenous vein, aneurysm, graft, pseudoaneurysm, coronary bypass) suggests a significantly higher prevalence with 14 such cases published in a variety of multinational journals during the period of 2006 to April 2007. The causes of this dramatic increase is likely multifactorial, however, in the author's opinion, likely reflects the increased sophistication and utilization of cross sectional imaging modalities.

Prediction of alternatively skipped exons and splicing enhancers from exon junction arrays

admin — Thu, 20 Nov 2008 15:02:35 -0500

Background:Alternative splicing of exons in a pre-mRNA transcript is an important mechanism which contributes to protein diversity in human. Arrays for detecting alternative splicing are available using several different probe designs, including those based on exon-junctions. In this work, we introduce a new method for predicting alternatively skipped exons from exon-junction arrays. Predictions based on our method are compared against controls and their sequences are analyzed to identify motifs important for regulating alternative splicing.Results:Our comparison of several alternative methods shows that an exon-skipping score based on neighboring junctions best discriminates between positive and negative controls.

Good adherence to HAART and improved survival in a community HIV/AIDS treatment and care programme: the experience of The AIDS S

admin — Thu, 20 Nov 2008 14:01:56 -0500

Background:Poor adherence to highly active antiretroviral therapy (HAART) may result in treatment failure and death. Most reports of the effect of adherence to HAART on mortality come from studies where special efforts are made to provide HAART under ideal conditions. However, there are few reports of the impact of non-adherence to HAART on mortality from community HIV/AIDS treatment and care programmes in developing countries. We therefore conducted a study to assess the effect of adherence to HAART on survival in The AIDS Support Organization (TASO) community HAART programme in Kampala, Uganda.

GenVec Announces Interim Survival Data In Pivotal Trial Of TNFerade™ In Locally Advanced Pancreatic Cancer

admin — Thu, 20 Nov 2008 12:00:50 -0500

GenVec, Inc. (Nasdaq:GNVC) announced today top-line results of an interim analysis from its ongoing Phase III Pancreatic Cancer Clinical Trial with TNFerade™ (PACT) in patients with locally advanced pancreatic cancer.

Children Of Centenarians Live Longer, Have Lower Risk Of Heart Disease, Stroke, Diabetes

admin — Thu, 20 Nov 2008 12:00:47 -0500

A recent study appearing in the November issue of Journal of American Geriatrics Society revealed that centenarian offspring (children of parents who lived to be at least 97 years old) retain important cardiovascular advantages from their parents compared to a similarly-aged cohort.

Randomized Phase 2 Study Of IMC-A12 For HER2-Expressing Advanced Breast Cancer Commences Patient Enrollment

admin — Thu, 20 Nov 2008 12:00:44 -0500

ImClone Systems Incorporated (NASDAQ: IMCL), a global leader in the development and commercialization of novel antibodies to treat cancer, today announced that its disease-directed randomized Phase 2 clinical trial of IMC-A12 in patients with previously treated HER2-expressing locally advanced or metastatic breast cancer has commenced patient enrollment.

General Opital Council News - 20th November, 2008

admin — Thu, 20 Nov 2008 11:00:42 -0500

Members bid farewell to Council chairman Council met on 20 November 2008 at the Durrants Hotel, London. The meeting was Rosie Varley's last as chairman, having served in the role for ten years.

Depuy Mitek Launches Healix™ Br With Biocryl(R) Rapide™, Leading U.S. Biocomposite Material For Shoulder, Knee Implants

admin — Thu, 20 Nov 2008 11:00:38 -0500

DePuy Mitek, Inc., a leading orthopedics sports medicine company, today announced the launch of the HEALIX™ BR Dual Threaded Anchor System, the first suture anchor for arthroscopic rotator cuff repair made with the company's proprietary BIOCRYL® RAPIDE™ biocomposite material, shown in pre-clinical trials to resorb and promote bone formation within the implant profile2.

General Optical Council Registration Fees Go Up For First Time In Four Years - UK

admin — Thu, 20 Nov 2008 11:00:33 -0500

The GOC today announced that the annual retention fee for 2009/10 is rising from Â£169 to Â£219. This is the first time in four years that the cost of GOC registration has gone up. The new fee amount was agreed by Council at its November meeting, and applies to the next retention period, which runs from 1 April 2009 - 31 March 2010.

King College Announces It Will Open A Medical School - Bristol Herald Courier

admin — Thu, 20 Nov 2008 10:51:30 -0500

Bristol Herald Courier